STUDY: Tirzepatide vs semaglutide head-to-head trial just published

SURPASS-2 update came out yesterday. TL;DR — at 72 weeks, tirzepatide 15mg outperformed semaglutide 1.0mg by about 6 percentage points on weight loss (~22% vs ~15%) in adults with type 2 diabetes.

With the caveat that this isn't a head-to-head at the highest sema dose (2.4 mg Wegovy). But still — this is the cleanest comparison data we have so far. Link to the abstract in comments.